Antenatal psychological interventions may ameliorate postpartum depression: a systematic review and meta-analysis.
J Obstet GynaecolApr 24, 2026 (epub)
Yuying Chen, Bin Zhao, Zhaoyuan Chen
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In 30 seconds
This systematic review and meta-analysis evaluated the impact of antenatal psychological interventions on postpartum depression in pregnant women without severe mental illness. Analyzing data from 10 randomized controlled trials involving 6,700 participants, the study found a significant reduction in postpartum depression incidence in the intervention group (OR = 0.73, 95% CI [0.57-0.95], P = 0.02).
Key findings
- The incidence rate of postpartum depression was significantly reduced in the intervention group (OR = 0.73, 95% CI [0.57-0.95], P = 0.02).
- Scores on the Edinburgh Postnatal Depression Scale were lower in the intervention group compared to controls.
- Intervention participants reported lower levels of anxiety and perceived stress than those receiving routine care.
Why it matters
Postpartum depression can adversely affect maternal and infant health. This study highlights the potential of psychological interventions during pregnancy to mitigate these risks, emphasizing the importance of mental health support in prenatal care.