A randomized controlled trial on the effect of Gushukang on bone mineral density in perimenopausal and postmenopausal women.
Lili Liu, Xiangyan Ruan, Muqing Gu et al.
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In 30 seconds
This randomized controlled trial investigated the effects of Gushukang on bone mineral density (BMD) in 156 perimenopausal and postmenopausal women. After 6 months, the combination therapy group showed a significant increase in BMD compared to baseline (p < 0.01), while hormone therapy also improved BMD but to a lesser extent.
Key findings
- The combination therapy group had a significant increase in BMD after 6 months (p < 0.01).
- FSH and LH levels decreased significantly in the hormone therapy and combination groups (p < 0.05).
- E2 levels increased significantly in the hormone therapy and combination groups (p < 0.05).
- No significant differences in liver or kidney function were found in any group.
Why it matters
The study highlights the potential of Gushukang and hormone therapy in improving bone mineral density in women undergoing menopause, which is crucial for preventing osteoporosis and related fractures.