When Rare Meets Young: Pediatric Presentation of Desmoplastic Fibroblastoma.
Mario Della Mura, Joana Sorino, Anna Colagrande et al.
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Case in brief
A 12-year-old boy presented with a 4.2 cm subcutaneous mass in the left thigh. Histologic examination showed a well-circumscribed proliferation of stellate and/or spindle-shaped fibroblasts in abundant, hypovascular collagenous stroma, consistent with desmoplastic fibroblastoma (collagenous fibroma), a benign soft-tissue tumor that predominantly occurs in adults. The lesion was completely excised, and the patient remained free of recurrence two years later.
What made this case unusual
The tumor occurred in a child, whereas desmoplastic fibroblastoma predominantly affects adults; the report notes only 5 additional pediatric cases.
Diagnostic / clinical pearl
Include desmoplastic fibroblastoma in the differential diagnosis of benign fibroblastic or fibrohistiocytic soft-tissue lesions, even in pediatric patients.