Nerve Transfer for Intrinsic Hand Dysfunction in Brown-Vialetto-Van Laere Syndrome: Expanding the Role of SETS in Motor Neuronopathies.
Luis Guilherme Rosifini Alves Rezende
✦ AI-curated · Sources linked
Case in brief
A patient with Brown-Vialetto-Van Laere syndrome presented with intrinsic hand dysfunction due to isolated postganglionic ulnar motor dysfunction. Electroneuromyography confirmed the preservation of the median nerve, making the patient a candidate for surgical intervention. A supercharged end-to-side anterior interosseous-to-ulnar motor nerve transfer was performed, resulting in restored hand function within 6 months and sustained improvement at 5-year follow-up.
Diagnostic / clinical pearl
Electroneuromyography can help identify surgical candidates in patients with motor neuronopathies by revealing preserved donor pathways.
Why it matters
This case demonstrates the potential for nerve transfer techniques, like SETS, to be applied in progressive motor neuron disorders, expanding treatment options beyond traditional conservative management.