Endoscopic Ultrasound-Guided Transluminal Drainage of Walled-Off Necrosis Using Naso-Cystic Drain With Metal Stent Versus Metal Stent Alone: A Randomized Controlled Pilot Study.
PancreasSep 1, 2026 (epub)
Nilanjan Kar, Surinder S Rana, Rajesh Gupta et al.
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In 30 seconds
This randomized controlled pilot study evaluated the efficacy of endoscopic ultrasound-guided drainage with nasocystic drainage (NCD) versus without NCD in 40 patients with symptomatic walled-off necrosis (WON). Clinical success at day 3 was 55% in the NCD group compared to 45% in the non-NCD group (P=0.527), indicating no significant difference in outcomes.
Key findings
- Clinical success at day 3 was 55% in the NCD group versus 45% in the non-NCD group (P=0.527).
- The median hospital stay was significantly shorter in the non-NCD group (P=0.038).
- Technical success was achieved in all patients.
- Readmission and complication rates were similar across both groups.
Why it matters
Understanding the effectiveness of nasocystic drainage in conjunction with standard treatment for walled-off necrosis can inform clinical decision-making and optimize patient management strategies.
What to keep in mind
The study's small sample size and baseline imbalance limit the generalizability of the findings.