Effects of Lactiplantibacillus plantarum KABP051 Probiotic on Body Composition, Microbiome and Mood in Healthy Overweight Adults.
J Med FoodMay 1, 2026 (epub)
Shawn Talbott, Bret Stephens, Julie Talbott et al.
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In 30 seconds
This randomized controlled trial evaluated the effects of Lactiplantibacillus plantarum KABP051 on body composition, microbiome, and mood in 60 healthy overweight adults over 12 weeks. The probiotic group showed significant reductions in body weight (1.97 ± 0.77 kg) and waist circumference (2.15 ± 0.81 cm) compared to placebo, alongside improvements in mood states.
Key findings
- Probiotic supplementation led to a weight reduction of 1.97 ± 0.77 kg compared to placebo.
- Waist circumference decreased by 2.15 ± 0.81 cm in the probiotic group versus placebo.
- Significant improvements in mood states were observed, with P-values of 0.015, 0.014, and 0.016 for fatigue and confusion sub-scores.
Why it matters
The findings suggest that Lactiplantibacillus plantarum KABP051 may offer a dual benefit of aiding weight loss and enhancing mood, which could be relevant for managing obesity and associated mental health issues.