Low-grade myofibroblastic sarcoma of the orbit in a 68-year-old woman: a case report.
Andreas Worm Bendtsen, Peter Bjerre Toft, Kåre Fugleholm et al.
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Case in brief
A 68-year-old woman presented with progressive, painless left eye protrusion, accompanied by motility restrictions and dilated conjunctival vessels. Imaging revealed a well-defined orbital tumor associated with the lateral rectus muscle. Biopsy showed a spindle cell tumor consistent with low-grade myofibroblastic sarcoma, confirmed by immunohistochemistry and genetic analysis. The tumor was successfully treated with en bloc resection, with no recurrence noted after 18 months.
Diagnostic / clinical pearl
Histological and immunohistochemical evaluation is crucial for diagnosing low-grade myofibroblastic sarcoma, particularly in cases of unilateral proptosis.