Dramatic Morphometabolic Response to Bevacizumab-Based Chemotherapy After Immunotherapy Failure in Malignant Pleural Mesothelioma on FDG PET.

Clin Nucl MedApr 16, 2026 (epub)
Case ReportOncology (Medical)Radiology (Diagnostic)

Kevser Oksuzoglu, Lutfu Perktas, Hasan Onner et al.

✦ AI-curated · Sources linked

Case in brief

A patient with epithelioid-type malignant pleural mesothelioma exhibited primary resistance to immunotherapy with ipilimumab and nivolumab. Following this treatment failure, the patient was switched to a chemotherapy regimen consisting of bevacizumab, pemetrexed, and carboplatin. This change resulted in a significant metabolic response as observed on 18F-FDG PET/CT imaging.

Diagnostic / clinical pearl

Clinicians should consider alternative chemotherapy regimens, such as bevacizumab-based therapy, in cases of immunotherapy resistance in malignant pleural mesothelioma.

Source

PubMed · PMID 42080609

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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