FDG PET/CT in a Case of Diffuse Esophageal Squamous Cell Carcinoma.

Clin Nucl MedApr 21, 2026 (epub)

Jun Zhang, Aisheng Dong, Yang Wang

✦ AI-curated · Sources linked

Case in brief

A patient with poorly differentiated esophageal squamous cell carcinoma presented with diffuse involvement of the entire esophagus. FDG PET/CT revealed irregular thickening of the esophageal wall and intense FDG uptake, with a maximum standardized uptake value (SUV max) of 15. Additionally, multiple FDG-avid lymph nodes and osteolytic bone metastases were identified, highlighting the advanced nature of the disease.

What made this case unusual

The case is notable for the diffuse FDG uptake pattern in esophageal cancer, which is typically characterized by focal intense uptake.

Diagnostic / clinical pearl

Clinicians should be aware that diffuse FDG uptake in esophageal cancer may indicate advanced disease, differing from the more common focal uptake patterns.

Why it matters

Recognizing atypical imaging findings can aid in the accurate assessment and staging of esophageal cancer, potentially influencing management decisions.

Source

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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