NUT Carcinoma of the Lacrimal Apparatus Presenting as a Rapidly Enlarging Medial Canthal Mass: A Case Report.
Pratiksha Vidhe Sharma, Harshala H Lokhande, Shruti Vimal
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Case in brief
A 26-year-old woman presented with a rapidly enlarging nasal canthal mass causing vision obstruction in her left eye, accompanied by redness and pruritus. Examination revealed a 4 × 3 cm lacrimal mass compressing the extraocular muscles. Histological analysis showed nests of small round blue cells with keratinization, and immunohistochemistry confirmed NUT carcinoma through positive NUTM1 expression.
Diagnostic / clinical pearl
NUT carcinoma should be considered in young patients with rapidly enlarging medial canthal masses, necessitating prompt biopsy and immunohistochemical evaluation.
Why it matters
This case highlights the importance of recognizing rare malignancies like NUT carcinoma in atypical presentations, which can lead to timely diagnosis and management.