Postoperative antibiotics do not reduce surgical site infections after clean thyroid and breast surgery: A randomised controlled trial from a resource-constrained setting.
Trop DoctMay 7, 2026 (epub)
M Mohammed Imran, Jayesh Chavda, Saket Shekhar et al.
✦ AI-curated · Sources linked
In 30 seconds
This randomized controlled trial evaluated the impact of postoperative antibiotics on surgical site infections (SSIs) in adults undergoing elective clean thyroid and breast surgeries in a public hospital in central India. The study found that postoperative antibiotics did not significantly reduce SSIs compared to a single pre-incision prophylactic dose.
Key findings
- No significant difference in 30-day surgical site infections between the antibiotic group and the control group.
- Patients received either three days of antibiotics or a single pre-incision dose.
- The study highlights unnecessary antimicrobial exposure in resource-constrained settings.
Why it matters
Understanding the effectiveness of postoperative antibiotics in clean surgeries is crucial for optimizing antibiotic use and minimizing resistance, especially in resource-limited environments.