Invasive Micropapillary Carcinoma of the Breast with an Encapsulated-Like Pattern: An Unreported Entity?
Yusuf Aboul-Nasr, Clare F Hartman, Marilin Rosa et al.
✦ AI-curated · Sources linked
Case in brief
A 71-year-old woman presented with a palpable left breast mass. MRI identified a 10 cm enhancing oval mass, and core needle biopsy confirmed invasive carcinoma with micropapillary features. Following neoadjuvant chemotherapy, a mastectomy revealed an 11 cm well-circumscribed mass with a fibrous capsule, characterized by tubulo-micropapillary structures and rare lymphovascular invasion. Sentinel lymph nodes were negative.
What made this case unusual
The case describes invasive micropapillary carcinoma exhibiting an encapsulated-like pattern, which has not been previously reported.
Diagnostic / clinical pearl
Clinicians should consider the possibility of invasive micropapillary carcinoma presenting with an encapsulated appearance, as this may lead to diagnostic challenges.
Why it matters
Recognizing this atypical presentation can improve diagnostic accuracy and management strategies for similar cases in the future.