5-Year Outcomes of the Dissected Aorta Repair Through Stent (DARTS) Implantation Trial.
Ann Thorac SurgMay 5, 2026 (epub)
Clinical ResearchCardiothoracic Surgery
Ryaan El-Andari, Sabin J Bozso, Jeevan Nagendran et al.
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In 30 seconds
The DARTS trial evaluated 5-year outcomes in patients with acute DeBakey Type I dissection treated with the Artivion AMDS hybrid prosthesis. In this clinical trial involving 46 patients, 80% remained free from any aortic procedure, and 94% were free from reoperation. The study highlights favorable aortic remodeling over the follow-up period.
Key findings
- 12 patients (26.1%) died before the 5-year follow-up.
- New stroke occurred in 10 patients (21.7%).
- 75%-95% of false lumens were thrombosed in zones 0-5 by 5 years.
- 80% of patients were free from any aortic procedure at 5 years.
Why it matters
Understanding long-term outcomes in patients with acute DeBakey Type I dissection is crucial for clinicians to assess the effectiveness of surgical interventions and manage patient expectations regarding recovery and potential complications.