A Rare Case Report of Renal Hilar Teratoma Associated With a Well-Differentiated Neuroendocrine Tumor and High-Grade Upper Urinary Tract Urothelial Carcinoma.
Birgül Tok, Doğan Sabri Tok, Erhan Demirelli et al.
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Case in brief
A 70-year-old man presented with a renal hilar mature teratoma, which contained a well-differentiated neuroendocrine tumor alongside a high-grade upper urinary tract urothelial carcinoma. Imaging revealed distinct lesions in the renal hilum and distal ureter. Histopathological analysis confirmed the presence of these mixed neoplasms, highlighting the complexity of the diagnosis. The case was managed with a multidisciplinary approach.
What made this case unusual
The coexistence of a mature teratoma with a well-differentiated neuroendocrine tumor and high-grade urothelial carcinoma in the renal hilar region is exceptionally rare.
Diagnostic / clinical pearl
Clinicians should consider teratomas in the differential diagnosis of renal hilar masses in adults, especially when atypical presentations are observed.
Why it matters
This case emphasizes the importance of thorough radiologic and pathologic evaluation in diagnosing complex retroperitoneal masses, which can present diagnostic challenges.