Risk factors for bleeding after endoscopic retrograde cholangiopancreatography: a systematic review and meta-analysis.
Aamir Saeed, Hina Akbar, Yasi Xiao et al.
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In 30 seconds
This systematic review and meta-analysis examined risk factors for post-endoscopic retrograde cholangiopancreatography (ERCP) bleeding in 149,870 patients. The analysis identified several significant risk factors, including anticoagulation therapy (OR, 2.75) and coagulopathy (OR, 11.01), which are associated with increased odds of bleeding following the procedure.
Key findings
- Anticoagulation therapy was associated with an odds ratio of 2.75 for post-ERCP bleeding.
- Coagulopathy significantly increased the odds of bleeding with an OR of 11.01.
- Cirrhosis and hemodialysis were also identified as significant risk factors for post-ERCP bleeding.
- Male gender was associated with increased odds of post-ERCP bleeding (OR, 1.24).
Why it matters
Understanding the risk factors for post-ERCP bleeding is crucial for clinicians to identify high-risk patients, optimize informed consent, and implement effective prevention and management strategies.