Open Versus Robot-assisted Kidney Transplantation in Adults with End-stage Kidney Disease (ORAKTx): A Randomised Open-label Trial.
Eur UrolMay 8, 2026 (epub)
Milla Ortved, Julia Dagnæs-Hansen, Hein V Stroomberg et al.
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In 30 seconds
The ORAKTx trial compared robot-assisted kidney transplantation (KTx) to open KTx in adults with end-stage kidney disease. Conducted as a randomised open-label trial, it found that major surgical complications occurred in 13% of the robotic group versus 25% in the open group, although this difference was not statistically significant (p = 0.2).
Key findings
- Major surgical complications occurred in 25% of the open KTx group compared to 13% in the robotic group.
- Vascular complications were reported in 19% of the open KTx group versus 9.4% in the robotic group.
- The risk difference for major complications was -11% with a 95% CI of -26 to 3.4.
- The study had a modest sample size with limitations including a single-centre design.
Why it matters
Understanding the comparative outcomes of robotic versus open kidney transplantation is crucial for surgical decision-making, particularly regarding postoperative complications and patient recovery.
What to keep in mind
The study's limitations include a single-centre design, lack of blinding, and a modest sample size.