Clinical outcomes of benign prostatic hyperplasia surgery in men with detrusor underactivity versus normal contractility: a systematic review and meta-analysis.
Alejandro Calvillo-Ramirez, Luis A Esparza-Miranda, Ana Paulina Casas-Huesca et al.
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In 30 seconds
This systematic review and meta-analysis evaluated surgical outcomes in men with benign prostatic hyperplasia (BPH) and detrusor underactivity (DUA) compared to those with normal contractility (NC). Analyzing 14 studies with 4,345 patients, the study found that postoperative urinary retention occurred more frequently in the DUA group (OR 1.63, 95% CI 1.21-2.20), while major complications were similar between groups.
Key findings
- Postoperative urinary retention was more frequent in the DUA group (OR 1.63, 95% CI 1.21-2.20).
- Minor complications occurred more often in patients with DUA (OR 1.31, 95% CI 1.08-1.59).
- Functional outcomes, including changes in Qmax and PVR, were comparable between DUA and NC groups at 6 months.
Why it matters
Understanding the impact of detrusor underactivity on surgical outcomes in BPH patients is crucial for clinicians to manage expectations and postoperative care effectively. This study provides insights into the safety and effectiveness of BPH surgery in this population.
What to keep in mind
Most available data are retrospective, and definitions of detrusor underactivity vary across studies.