A novel hemizygous missense variant in the BEND2 gene is associated with nonobstructive azoospermia.

Asian J AndrolMay 12, 2026 (epub)
Case ReportMedical GeneticsUrology

Chun-Hai Luo, Zi-Qi Yu, Hong-Yi Wang et al.

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Condensed from the publisher's abstract. An xxcode editorial summary of this publication has not been generated yet.

From the abstract

Nonobstructive azoospermia (NOA), the most severe form of male infertility, frequently arises from genetic defects that disrupt spermatogenesis. In this study, a novel hemizygous missense variant (NM_001184767.2 [c.G1069A; p.V357I]) is identified in the X-linked BEN domain-containing 2 ( BEND2 ) gene of a patient with NOA characterized by spermatocyte maturation arrest.

Source

PubMed · PMID 42116563

Published in Asian J Androl. The text above is extracted from the publisher's own abstract and has not been edited by xxcode. For clinical decisions, review the original publication.

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