Effect of Perioperative Sucralfate Administration on Pain Control After Tonsillectomy: A Systemic Review and Meta-Analysis.
Ann Otol Rhinol LaryngolMay 13, 2026 (epub)
Clinical ResearchOtolaryngology (ENT)
Do Hyun Kim, David W Jang, Se Hwan Hwang
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In 30 seconds
This systematic review and meta-analysis evaluated the impact of perioperative intraoral sucralfate on postoperative pain following tonsillectomy. The analysis included 13 studies and found that sucralfate significantly increased the proportion of patients reporting no or mild throat pain and otalgia, while also improving mucosal healing at 5 to 7 days.
Key findings
- Sucralfate increased the proportion of patients with no or mild throat pain and otalgia.
- It improved mucosal healing at 5 to 7 days post-surgery.
- Sucralfate reduced analgesic consumption and time to resume >50% of a regular diet.
Why it matters
Effective pain management and quicker recovery are crucial in postoperative care. This study suggests that sucralfate may enhance patient comfort and expedite dietary resumption, which can improve overall recovery after tonsillectomy.