Cytomegalovirus Induced Infectious Crystalline Keratopathy After Penetrating Keratoplasty.
Mehrnaz Atighehchian, Zahra Jafari, Siamak Zarei-Ghanavati et al.
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Case in brief
A 55-year-old male with a history of multiple penetrating keratoplasties presented with decreased vision and needle-like branching corneal lesions. Initial smear and culture tests were negative, but polymerase chain reaction confirmed Cytomegalovirus (CMV) infection. Following an adjustment in immunosuppressive therapy and initiation of antiviral treatment, the patient showed a favorable clinical response.
Diagnostic / clinical pearl
Clinicians should consider CMV infection in cases of infectious crystalline keratopathy that do not respond to standard antimicrobial treatments, especially in immunosuppressed patients.
Why it matters
This case highlights the utility of polymerase chain reaction testing for accurate diagnosis of CMV keratitis, which can significantly impact management strategies.