SGLT-2 Use and Hypoglycemic Ketoacidosis.
Benjamin A Johnson, Areeba A Abid, Luz M Silverio
✦ AI-curated · Sources linked
Case in brief
A patient presented with severe hypoglycemic nondiabetic ketoacidosis, a rare variant of diabetic ketoacidosis. The diagnostic challenge arose due to the absence of hyperglycemia, which is typically expected in such cases. The patient required insulin therapy for resolution of the ketoacidosis, highlighting the need for awareness of atypical presentations in emergency settings.
What made this case unusual
The case exemplifies severe hypoglycemic nondiabetic ketoacidosis, which is uncommon and can lead to diagnostic confusion.
Diagnostic / clinical pearl
Clinicians should consider nondiabetic ketoacidosis in patients presenting with ketoacidosis symptoms, even in the absence of hyperglycemia.
Why it matters
Recognizing atypical presentations of ketoacidosis can prevent delays in treatment and improve patient outcomes in emergency medicine.