Contemporary systematic review and meta-analysis of outcomes associated with femoropopliteal above-the-knee nonautologous surgical bypass.
J Vasc SurgMay 14, 2026 (epub)
Clinical ResearchVascular Surgery
Anne M Ryschon, Ami Sood, Abigail M Garner et al.
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In 30 seconds
This systematic review and meta-analysis evaluated outcomes of above-the-knee femoropopliteal nonautologous surgical bypass in 2083 patients. The study found primary patency rates of 80% at 12 months and 61% at 36 months. The analysis provides a contemporary benchmark for clinicians considering surgical bypass for long-segment or heavily calcified lesions.
Key findings
- 12-month primary patency rate was 80% (95% CI, 0.77-0.82).
- 36-month secondary patency rate was 68% (95% CI, 0.56-0.78).
- 12-month limb salvage rate was 97% (95% CI, 0.91-1.00).
- Mortality rates increased from 7% at 6 months to 24% at 36 months.
Why it matters
Understanding the contemporary outcomes of nonautologous surgical bypass is crucial for clinicians when evaluating treatment options for patients with femoropopliteal disease, particularly in cases where endovascular therapy may not be suitable.