Hepatic Perfusion-Related Pseudolesion Mimicking Metastasis on 68 Ga-PSMA PET/CT.
Kevser Oksuzoglu, Lutfu Perktas, Hasan Onner et al.
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Case in brief
A patient with prostate cancer underwent 68 Ga-PSMA PET/CT, revealing a wedge-shaped area of increased PSMA uptake in segment VIII of the liver. MRI showed no focal lesion but indicated mild diffusion hyperintensity and transient arterial hyperenhancement. These imaging characteristics suggested a perfusion-related pseudolesion rather than metastasis, leading to a non-invasive management approach.
Diagnostic / clinical pearl
Clinicians should consider perfusion-related pseudolesions in the liver when interpreting 68 Ga-PSMA PET/CT findings, especially in the absence of corresponding MRI lesions.