Solitary Pancreatic Metastasis From Dermatofibrosarcoma Protuberans: A Diagnostic Challenge Mimicking Primary Pancreatic Carcinoma.

Clin Nucl MedMay 14, 2026 (epub)
Case ReportOncology (Medical)

Zeyu Zhang, Changjing Zuo, Xia Zhou et al.

✦ AI-curated · Sources linked

Case in brief

A 56-year-old man presented with hyperglycemia and weight loss. Imaging suggested a pancreatic head mass resembling primary pancreatic carcinoma. 18 F-FDG PET/CT confirmed a hypermetabolic lesion without distant metastasis. After a Whipple procedure, histopathology and immunohistochemistry revealed a solitary pancreatic metastasis from dermatofibrosarcoma protuberans, highlighting the diagnostic challenges in differentiating it from primary pancreatic cancer.

Diagnostic / clinical pearl

Clinicians should consider the possibility of solitary pancreatic metastases in patients with a history of sarcoma, as they can mimic primary pancreatic carcinoma on imaging.

Source

PubMed · PMID 42149608

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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