An Expanded Access Program With NexoBrid for Treatment of Acute Deep Partial and Full Thickness Burn Injuries in Adult and Pediatric Patients.
J Burn Care ResSep 8, 2026
Steven A Kahn, John Schulz, Tam Pham et al.
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In 30 seconds
This multicenter clinical trial evaluated the expanded access program for NexoBrid in treating acute deep partial and full thickness burn injuries in 239 patients (215 adults, 24 pediatric) across 23 burn centers. The study found that eschar removal was achieved in 95% of adults and 100% of pediatric patients within 4 hours, with a median hospital stay of 10 days.
Key findings
- Eschar removal was achieved in 95% of adults and 100% of pediatric patients within 4 hours.
- Surgical excision was performed in 4% of adults, with no pediatric cases requiring it.
- Wound closure occurred by a median of 22 days for adults and 28 days for pediatric patients.
Why it matters
The findings support the use of NexoBrid as an effective treatment option for burn injuries, potentially improving patient outcomes and reducing the need for surgical interventions. Understanding its efficacy can enhance clinical decision-making in burn care.