Eosinophilic Myenteric Ganglionitis in a Newborn: Case Report.

Pediatr Dev PatholMay 19, 2026 (epub)
Case ReportPediatricsGeneral SurgeryPathology (Anatomic & Clinical)

Luz F Sua, María Del Mar Conde, Juan Carlos Bravo et al.

✦ AI-curated · Sources linked

Case in brief

A male newborn presented with intestinal obstruction and was found to have intestinal malrotation. Histology showed colonic ganglion cells surrounded by a moderate eosinophilic infiltrate, consistent with eosinophilic myenteric ganglionitis. After surgical correction and protective diverting ileostomy, he improved progressively. At 18 months, contrast enema showed persistent old contrast medium in the dysfunctional sigmoid rectum, suggesting possible rectal motility impairment.

What made this case unusual

The report describes a newborn with both intestinal malrotation and eosinophilic myenteric ganglionitis, an association the authors identify as previously unreported.

Diagnostic / clinical pearl

In a newborn with obstructive symptoms, histological assessment of the intestinal wall can identify myenteric eosinophilic inflammation even when the clinical picture suggests mechanical obstruction.

Source

PubMed · PMID 42154483

Published in Pediatr Dev Pathol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

ShareTelegramLinkedIn

AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

More in Pediatrics

Clinical ResearchPreventive Medicine / Public Health

2025 National Guidelines on the Mediterranean Diet: Executive Summary of a Joint Report by Italian Scientific Societies and the National Institute of Health Task Force on Clinical Practice Guidelines.

This systematic review and practice guideline, developed by a multidisciplinary panel using NUTRIGRADE, assessed Mediterranean diet evidence across nine health domains and one economic domain.

Nutr RevNov 12, 2026Read summary
Clinical ResearchOrthopedic Surgery

Prevention of Venous Thromboembolism after Total Hip or Knee Replacement.

This multicenter randomized comparative-effectiveness noninferiority trial compared 30 days of aspirin, warfarin, or rivaroxaban for VTE prophylaxis after elective total hip or knee arthroplasty.

N Engl J MedNov 12, 2026Read summary
Clinical ResearchAnesthesiology

Effect of discontinuing antihypertensives on perioperative hypotension in older patients before non-cardiac surgery: multicentre, randomised, double blind, controlled trial.

This multicentre, randomised, double blind, placebo controlled trial assessed whether withholding ACE inhibitors or ARBs on the morning of surgery reduces perioperative hypotension in older adults undergoing non-cardiac…

BMJNov 11, 2026Read summary

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.