Incidence and Progression of Glaucoma Following Boston Type 1 Keratoprosthesis: A Systematic Review and Meta-Analysis.
Abdelrahman Abu Osba, Korolos Sawires, Mostafa Bondok et al.
✦ AI-curated · Sources linked
In 30 seconds
This systematic review and meta-analysis evaluated the incidence and progression of glaucoma following Boston Type 1 Keratoprosthesis (KPro) implantation in 1,482 eyes. The pooled incidence of postoperative glaucoma events was found to be 25.6%, with a significant proportion of eyes experiencing either de novo glaucoma (31.1%) or progression of pre-existing glaucoma (37.7%).
Key findings
- The pooled incidence of any postoperative glaucoma events was 25.6% (95% CI: 18.1-34.8%).
- De novo glaucoma occurred in 31.1% of eyes (95% CI: 20.6-43.9%).
- Progression of pre-existing glaucoma was observed in 37.7% of eyes (95% CI: 17.9-62.6%).
- Ocular hypertension without confirmed glaucoma was noted in 17.1% of eyes (95% CI: 5.6-41.9%).
Why it matters
Understanding the incidence and progression of glaucoma after KPro implantation is crucial for clinicians to make informed treatment decisions and improve long-term visual outcomes in patients at high risk for this complication.
What to keep in mind
The certainty of evidence is very low due to significant heterogeneity and variability in diagnostic definitions across studies.