Inflammatory Myofibroblastic Tumour of Head and Neck: A Systematic Review Plus Meta-Analysis.
Clin OtolaryngolMay 21, 2026 (epub)
Alireza Sharifi, Mohaddeseh Zojaji, Narges Badragheh et al.
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In 30 seconds
This systematic review and meta-analysis evaluated 22 studies involving 337 patients with inflammatory myofibroblastic tumors in the head and neck. The study found that surgical resection was the most common treatment, with a recurrence rate of 21.6%. The tumors predominantly originated from the sinonasal space, and immunohistochemical markers such as vimentin and SMA were frequently positive.
Key findings
- Recurrence occurred in 21.6% of patients after treatment.
- Metastases were reported in 8.8% of cases.
- 40.1% of tumors originated from the sinonasal space.
- Most tumors were positive for vimentin and SMA.
Why it matters
Understanding the clinical presentation and treatment outcomes of inflammatory myofibroblastic tumors can aid clinicians in diagnosis and management, particularly in distinguishing these tumors from other head and neck lesions.