Pharmacological, psychosocial, and brain stimulation interventions in oncologic populations with mental disorders: An umbrella review.
Michele Fornaro, Chiara Di Lorenzo, Domenico De Berardis et al.
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In 30 seconds
This umbrella review analyzed 82 meta-analyses of randomized controlled trials assessing pharmacological, psychosocial, and brain stimulation interventions for mental disorders in cancer patients. The review found that mindfulness-based stress reduction significantly outperformed standard treatment for anxiety in lung cancer, with a Hedges' g of -1.46. Most studies focused on major depressive and anxiety disorders.
Key findings
- Mindfulness-based stress reduction significantly outperformed standard treatment for anxiety in lung cancer (Hedges' g=-1.46).
- Psychotherapy for women post-mastectomy was inferior to waiting list in treating anxiety (G=0.33).
- 48.67% of studies focused on major depressive disorders among oncologic populations.
- Meta-regression indicated psychotherapies may benefit females more than males.
Why it matters
Understanding the efficacy of various interventions for mental health disorders in cancer patients is crucial for improving patient care. This review highlights the need for effective treatment strategies tailored to this population, particularly for anxiety and depression.