Pregnancy Associated Atypical Onychopapilloma: A Novel Presentation of an Emerging Entity in Dermatopathology.
Carli Tucci, Erika Koh, John A Carucci et al.
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Case in brief
A 37-year-old woman presented with a red longitudinal band on her left thumbnail that developed during her first trimester of pregnancy. The lesion was asymptomatic but increased in size, leading to a longitudinal excisional biopsy postpartum. Histopathology confirmed atypical onychopapilloma, showing features like acanthosis, papillomatosis, and cytologic atypia. The tumor was excised with Mohs micrographic surgery, and no recurrence was noted at 6-month follow-up.
What made this case unusual
This case highlights the occurrence of atypical onychopapilloma during pregnancy, an emerging entity in dermatopathology.
Diagnostic / clinical pearl
Clinicians should consider atypical onychopapilloma in pregnant patients presenting with longitudinal erythronychia, as it may exhibit atypical histopathological features.
Why it matters
Understanding the presentation of atypical onychopapilloma during pregnancy can aid in accurate diagnosis and management, expanding the knowledge base in dermatopathology.