Enabling real-world evidence for medication safety in pregnancy: Determinants of research participation and linked EHR data use.
Yanghong Jessika Hu, Elaine Yl Chan, Marcus DI Sipio et al.
✦ AI-curated · Sources linked
In 30 seconds
This systematic review examined determinants influencing pregnant women's participation in research and their willingness to share electronic health record (EHR) data. Analyzing 61 studies with 44,722 participants across 22 countries, the findings revealed that acceptability of EHR data sharing varied widely, influenced by trust, perceived benefits, and privacy concerns. The study highlights the importance of socio-technical factors in enhancing medication safety research.
Key findings
- Willingness to share EHR data varied widely from 22% to 100%, influenced by trust and governance safeguards.
- Facilitators for participation included perceived societal benefits, altruism, and quality communication with healthcare providers.
- Barriers included privacy concerns, recruitment logistics, and cultural factors affecting participation.
Why it matters
Understanding the factors that influence research participation and data sharing in pregnancy is crucial for developing effective real-world evidence initiatives. This knowledge can help improve medication safety and ensure equitable inclusion of pregnant women in health research.