A systematic review and meta-analysis of bacterial pathogen prevalence in acute and chronic rhinosinusitis: implications for empiric antibiotic therapy and antimicrobial stewardship.
Int J Infect DisMay 28, 2026 (epub)
Clinical ResearchOtolaryngology (ENT)
Hye Ok Kim, Suhyeon Ha, Jung Jae Shim et al.
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In 30 seconds
This systematic review and meta-analysis examined bacterial pathogen profiles in acute rhinosinusitis (ARS) and chronic rhinosinusitis (CRS) by analyzing 57 studies. The findings revealed that in ARS, methicillin-susceptible Staphylococcus aureus (MSSA) was the most prevalent pathogen at 20.5%, while in CRS, coagulase-negative staphylococci were most common at 24.3%.
Key findings
- MSSA was the most prevalent pathogen in ARS at 20.5%.
- Coagulase-negative staphylococci were most common in CRS at 24.3%.
- S. pneumoniae was relatively infrequent in CRS at 9.4%.
Why it matters
Understanding the distinct bacterial profiles in ARS and CRS is crucial for guiding appropriate antibiotic therapy and improving antimicrobial stewardship. Tailoring treatment strategies based on these differences can enhance patient outcomes.