Intramuscular myxoma with chondroid features: two cases expanding the morphological spectrum.
Bethany Batson, Azfar Neyaz, Lucas Da Gama Lobo et al.
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Case in brief
Two cases of intramuscular myxoma with chondroid features are presented. The first case involved a 64-year-old woman with a tumor in the triceps, exhibiting focal cartilaginous differentiation. The second case involved a 48-year-old woman with a tumor in the vastus medialis, showing a mix of myxoid and collagenous stroma with chondromyxoid matrix. Both tumors were deep intramuscular lesions with characteristic MRI findings.
What made this case unusual
The presence of chondroid and chondromyxoid matrix in intramuscular myxomas is atypical and has not been previously reported.
Diagnostic / clinical pearl
Clinicians should recognize that intramuscular myxomas can exhibit chondroid features, which may lead to misclassification as other neoplasms.
Why it matters
Awareness of this morphological variant is crucial for accurate diagnosis and management, preventing potential misdiagnosis of chondromyxoid tumors.