Risk factors for suicidal behaviour in people with dementia: A systematic review and meta-analysis.
J Affect DisordMay 29, 2026 (epub)
Yin-Ting Chen, Sobia Kausar, Antje Lindenmeyer et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the risk factors for suicidal behavior in people with dementia (PwD). It found that PwD have a 62% increased risk of suicidal behavior compared to non-dementia controls (pooled OR = 1.62; 95% CI 1.32-1.98). The study highlights specific vulnerabilities among younger patients and men.
Key findings
- Dementia is associated with a 62% increased risk of suicidal behavior compared to non-dementia controls.
- Younger patients with dementia are nearly three times more likely to die by suicide than older patients.
- Men with dementia have 28% higher odds of suicide attempts and 188% increased odds of suicide deaths compared to women.
- Social isolation and a history of depression are significant risk markers for suicidal behavior in PwD.
Why it matters
Understanding the heightened risk of suicidal behavior in people with dementia is crucial for clinicians. Identifying vulnerable subgroups can inform targeted prevention strategies and improve patient outcomes.