The association between endometrial thickness and ectopic pregnancy among women who underwent in vitro fertilization, systematic review and meta-analysis.
Mohammad Haddadi, Kyana Jafarabady, Pegah Rashidian et al.
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In 30 seconds
This systematic review and meta-analysis examined the relationship between endometrial thickness and ectopic pregnancy in women undergoing in vitro fertilization. The analysis included 20 studies, with seven contributing to the meta-analysis. A significant correlation was found, with a combined odds ratio of 0.81 (95% CI: 0.78-0.85; p < 0.001), indicating that thinner endometrial thickness is associated with a higher risk of ectopic pregnancy.
Key findings
- Thinner endometrial thickness correlates with increased risk of ectopic pregnancy.
- Combined odds ratio for ectopic pregnancy per unit decrease in endometrial thickness is 0.81.
- The analysis included 20 studies, with seven in the meta-analysis.
- Statistical significance was established with p < 0.001.
Why it matters
Understanding the association between endometrial thickness and ectopic pregnancy can help clinicians in risk stratification for women undergoing in vitro fertilization, potentially guiding monitoring and management strategies.
What to keep in mind
The findings should be interpreted cautiously due to the observational design, potential confounding, and publication bias.