Nodular Fasciitis of the Parotid Gland Mimicking Pleomorphic Adenoma: Cytological Features of a Diagnostic Pitfall.
Xiaobing Jin, Steven Hrycaj, Stephanie L Skala et al.
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Case in brief
A 19-year-old female presented with a mass in the parotid gland, initially diagnosed as a salivary gland neoplasm via fine needle aspiration. Subsequent examination of the surgically resected specimen revealed it to be nodular fasciitis, a rare occurrence in this location. Accurate diagnosis is essential for proper management.
What made this case unusual
Nodular fasciitis in the parotid gland is an atypical presentation, often mimicking pleomorphic adenoma, which can lead to diagnostic confusion.
Diagnostic / clinical pearl
Cytopathologists should be aware that nodular fasciitis can resemble pleomorphic adenoma in cytological samples, necessitating careful evaluation.
Why it matters
Utilizing ancillary studies, such as in situ hybridization for USP6 rearrangement, can aid in distinguishing nodular fasciitis from other salivary gland neoplasms.