Head and neck NUT carcinoma-radiotherapy dose, chemotherapy choice, and outcomes: lessons from a 7-year complete remission.

Strahlenther OnkolJun 1, 2026 (epub)
Case ReportOncology (Medical)Radiology (Diagnostic)Otolaryngology (ENT)Open access

Lara Schulz, Matthias Zähringer, Klaus-Henning Kahl et al.

✦ AI-curated · Sources linked

Case in brief

A 19-year-old male with locally advanced supraglottic NUT carcinoma presented with dysphagia and otalgia. After laser debulking and temporary tracheostomy, he received induction chemotherapy with cisplatin, doxorubicin, and ifosfamide, achieving a complete metabolic response. He then underwent definitive intensity-modulated radiotherapy (IMRT) to 73.2 Gy. Following consolidation chemotherapy, he has maintained complete remission for over 7 years, though he experiences persistent xerostomia and dysgeusia.

Diagnostic / clinical pearl

Timely multimodal treatment, including systemic therapy and definitive radiotherapy exceeding 50 Gy, can lead to durable remission in non-metastatic head and neck NUT carcinoma.

Source

PubMed · PMID 42223602Free full text on PubMed Central

Published in Strahlenther Onkol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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