Randomized Trial of Intensive Nurse-Led Follow‑Up Versus Standard Care in Inflammatory Bowel Disease.
Dig Dis SciJun 2, 2026 (epub)
Revital Barkan, Idan Goren, Maya Fischman et al.
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In 30 seconds
This randomized controlled trial assessed the impact of an intensive nurse-led follow-up program on patients with inflammatory bowel disease (IBD) starting advanced therapy. A total of 98 patients were randomized to either intensive follow-up or standard care. At week 52, IBD-Disk remission was achieved by 88% of patients in the intensive group compared to 64% in the standard care group (p=0.045).
Key findings
- At week 12, patients in the intensive group had a greater IBD-Disk reduction of 16.1 ± 22.9 compared to 10.1 ± 20.1 in the standard care group (p=0.09).
- 49% of patients in the intensive group achieved a robust response at week 12 compared to 21% in the standard care group (p=0.013).
- By week 52, 88% of patients in the intensive group achieved IBD-Disk remission versus 64% in the standard care group (p=0.045).
Why it matters
The study highlights the potential benefits of integrating intensive nurse-led follow-up in managing IBD, which may enhance patient quality of life and clinical outcomes. Understanding these dynamics can inform care strategies in gastroenterology.