Endoscopic ultrasound-guided gastroenterostomy vs surgical gastrojejunostomy for malignant gastric outlet obstruction: a systematic review and meta-analysis.
J Gastrointest SurgJun 1, 2026 (epub)
Mohamed Abosheisha, Mustafa Alqasem, Elmoatazbellah Nasr et al.
✦ AI-curated · Sources linked
In 30 seconds
This systematic review and meta-analysis evaluated endoscopic ultrasound-guided gastroenterostomy (EUS-GE) versus surgical gastrojejunostomy (SGJ) for malignant gastric outlet obstruction in 22,118 patients. EUS-GE demonstrated higher clinical success and faster recovery, with a significant reduction in procedure time by 93.8 minutes and fewer adverse events compared to SGJ.
Key findings
- EUS-GE had lower technical success (OR 0.25; P =.0002) but higher clinical success (OR 1.51; P =.04).
- EUS-GE resulted in a shorter procedure time by 93.8 minutes (P <.0001).
- Patients undergoing EUS-GE had a shorter hospital stay by 4.91 days (P <.0001).
- EUS-GE required fewer reinterventions (OR 0.39; P =.02) and had fewer adverse events (OR 0.39; P <.0001).
Why it matters
The findings suggest that EUS-GE may offer a safer and more efficient option for patients with malignant gastric outlet obstruction, potentially leading to improved patient outcomes and reduced healthcare costs.