Preoperative risk factors for postoperative pneumonia in patients with esophageal cancer: A systematic review and meta-analysis.
Tsuyoshi Harada, Hiroki Sato, Kazuki Okura et al.
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In 30 seconds
This systematic review and meta-analysis evaluated preoperative risk factors for postoperative pneumonia in patients undergoing esophagectomy for esophageal cancer. Analyzing 60 studies, it found that physical frailty, sarcopenia, and forced expiratory volume (FEV) were significant predictors of pneumonia, with physical frailty showing the highest odds ratio of 5.170.
Key findings
- Physical frailty was associated with an odds ratio of 5.170 for postoperative pneumonia.
- Sarcopenia had an odds ratio of 2.790 for pneumonia risk.
- Forced expiratory volume (FEV) was linked to an odds ratio of 2.730.
Why it matters
Understanding these risk factors can help clinicians identify high-risk patients and implement targeted preoperative interventions to reduce the incidence of postoperative pneumonia, a significant complication following esophagectomy.