Endoscopic Ultrasound-Guided Versus Transjugular Portal Pressure Measurements: Systematic Review and Meta-Analysis.
Rintaro Hashimoto, Tomohiro Tanaka, Kenneth J Chang
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In 30 seconds
This systematic review and meta-analysis evaluated the correlation between endoscopic ultrasound-guided portal pressure gradient (EUS-PPG) and invasive hemodynamic measurements in six prospective cohorts. The pooled correlation with hepatic venous pressure gradient (HVPG) was 0.82, and with direct portal venous pressure, it was 0.86. Technical success was reported at 95.3%, with adverse events occurring in 2.4% of procedures.
Key findings
- Pooled correlation of EUS-PPG with HVPG was 0.82 (95% CI, 0.72-0.89).
- Pooled correlation of EUS-based measurements with direct portal venous pressure was 0.86 (95% CI, 0.72-0.93).
- Technical success rate for EUS-PPG was 95.3%.
- Adverse events attributed to EUS-PPG occurred in 2.4% of procedures.
Why it matters
Understanding the correlation between EUS-PPG and invasive measurements is crucial for clinicians assessing portal hypertension. This method may offer a less invasive alternative for monitoring patients, potentially improving patient safety and comfort.
What to keep in mind
The evidence base is limited to six cohorts with 127 attempted procedures, and agreement data were described as limited.