Intraocular Pressure Changes Following Intraluminal Stent Removal From the Paul Glaucoma Implant: A Systematic Review and Meta-Analysis.
Am J OphthalmolJun 6, 2026 (epub)
Clinical ResearchOphthalmology
Chiao-Hsin Lan, Shu-I Pao, Hsiang-Lin Tseng et al.
✦ AI-curated · Sources linked
In 30 seconds
This systematic review and meta-analysis evaluated the impact of intraluminal stent removal from the Paul glaucoma implant on intraocular pressure (IOP) changes in 283 eyes. The analysis found a significant immediate IOP reduction of -9.09 mm Hg post-removal. The effect was more pronounced in patients with high pre-removal IOP (>21 mm Hg).
Key findings
- The pooled mean difference in IOP reduction post-stent removal was -9.09 mm Hg.
- In the high-IOP subgroup, the IOP reduction was -11.82 mm Hg.
- The low-IOP subgroup showed a reduction of -6.66 mm Hg.
- The incidence of clinically significant hypotony was low at 0.03.
Why it matters
Effective management of intraocular pressure is crucial in glaucoma treatment to prevent vision loss. This study highlights a safe intervention that can significantly lower IOP, particularly in patients with high baseline levels.