Successful treatment of abnormal sensation associated with restless legs syndrome in adrenoleukodystrophy using Gunggwijohyeoleum-Jeilgagam: A case report.
Sunghee Hong, Han-Gyul Lee, Seungwon Kwon et al.
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Case in brief
A 50-year-old man with adrenoleukodystrophy (ALD) and a 10-year history of refractory restless legs syndrome (RLS) presented with severe symptoms, including insomnia and gait impairment. Conventional treatments were ineffective. After 21 days of treatment with the herbal medicine Gunggwijohyeoleum-Jeilgagam, his RLS symptoms significantly improved, with a reduction in the International Restless Legs Syndrome Rating Scale score and increased sleep duration, effects lasting for 5 months post-treatment.
Diagnostic / clinical pearl
This case highlights the potential of herbal medicine as a complementary treatment for refractory restless legs syndrome in patients with neurodegenerative disorders when conventional therapies fail.