Increased Mucocutaneous FDG Activity in Paraneoplastic Pemphigus Associated With Follicular Dendritic Cell Sarcoma Transformed From Castleman Disease.

Clin Nucl MedJun 5, 2026 (epub)
Case ReportDermatologyOncology (Medical)

Yu Long, Yang Wang, Aisheng Dong

✦ AI-curated · Sources linked

Case in brief

A patient with paraneoplastic pemphigus presented with severe mucocutaneous blistering associated with pelvic follicular dendritic cell sarcoma, which had transformed from Castleman disease. FDG PET/CT imaging revealed intense activity in the oral cavity, heterogeneous skin activity, linear esophageal activity, focal anal activity, and varied pelvic tumor activity. The condition was managed with appropriate oncological treatment.

Diagnostic / clinical pearl

Clinicians should consider paraneoplastic pemphigus in patients presenting with hypermetabolic mucocutaneous lesions, particularly in the context of underlying malignancies.

Source

PubMed · PMID 42257568

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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