Intraosseous Sustained-Release Anesthetics Promote Early Ambulation and Functional Recovery After Total Knee Arthroplasty.

J ArthroplastyJun 9, 2026 (epub)

Junjie Huang, Sohaib Hasan Abdullah Ezzi, Song Wu et al.

✦ AI-curated · Sources linked

In 30 seconds

This randomized controlled trial evaluated the impact of intraosseous sustained-release anesthetics on early ambulation and functional recovery in 110 patients undergoing total knee arthroplasty (TKA). The study found that the group receiving intraosseous infiltration (LIA plus TIA) had significantly lower pain scores and greater walking distances compared to the local infiltration anesthesia group (LIA).

Key findings

  • Visual analog scale scores were significantly lower at days one and three in the LIA plus TIA group compared to the LIA group (P < 0.05).
  • Patient-controlled epidural analgesia time was significantly longer in the LIA plus TIA group (18.7 vs 14.8 hours, P < 0.001).
  • Walking distance was significantly greater on days one and three in the LIA plus TIA group compared to the LIA group (P < 0.05).
  • Flexion and range of motion were significantly higher at days one and three in the LIA plus TIA group compared to the LIA group (P < 0.05).

Why it matters

Effective pain management is crucial for recovery after total knee arthroplasty. This study suggests that intraosseous sustained-release anesthetics can enhance postoperative outcomes, potentially leading to quicker rehabilitation and improved patient satisfaction.

Source

Published in J Arthroplasty. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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