Efficacy and Safety of En-Bloc Laser Enucleation of the Prostate for Benign Prostatic Obstruction: An Evidence-Based Analysis of Clinical Studies.
J Invest SurgJun 9, 2026 (epub)
Clinical ResearchUrology
Jinze Li, Jing Liu, Puze Wang et al.
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In 30 seconds
This meta-analysis evaluated the efficacy and safety of En-Bloc laser enucleation versus standard techniques for benign prostatic obstruction in 9,397 participants. The En-Bloc technique demonstrated a significant reduction in enucleation time (MD -8.43) and a lower rate of major complications (odds ratio 0.62), indicating improved perioperative performance.
Key findings
- En-Bloc technique reduced enucleation time by a mean difference of -8.43 minutes.
- En-Bloc technique increased enucleation efficiency with a mean difference of 0.21.
- Operative time decreased by a mean difference of -4.70 minutes with En-Bloc.
- Major complication rates were lower with En-Bloc, with an odds ratio of 0.62.
Why it matters
Understanding the comparative effectiveness of surgical techniques for benign prostatic obstruction is crucial for optimizing patient outcomes. The En-Bloc technique may offer advantages in terms of efficiency and safety, which can influence surgical decision-making.