Approach to the patient: cases of hormonal management in older transgender and gender diverse adults.

J Clin Endocrinol MetabSep 16, 2026

Micol S Rothman, Jason O van Heesewijk, Danit Ariel et al.

✦ AI-curated · Sources linked

Case in brief

This article presents a case-based approach to managing older transgender and gender diverse (TGD) adults undergoing gender-affirming hormone therapy. It highlights the complexities of care in the context of age-related health issues such as neurocognitive disorders, cardiovascular disease, prostate cancer, bone health, and menopause. The discussion emphasizes the need for tailored management strategies due to the lack of specific guidelines for this population.

Diagnostic / clinical pearl

Clinicians should consider the unique health challenges faced by older TGD adults when managing hormone therapy, as age-related conditions may complicate treatment.

Why it matters

This case-based approach underscores the necessity for future research to develop evidence-based guidelines tailored to the needs of older TGD adults, enhancing their healthcare outcomes.

Source

Published in J Clin Endocrinol Metab. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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