Tumor-to-Tumor Metastasis Involving Vestibular Schwannoma: Case Report and Literature Review.
Patrick R Toyota, Celine D Hounjet, Eva Liu et al.
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Case in brief
A 55-year-old female with a history of invasive ductal breast carcinoma presented with unilateral hearing loss and gait disturbance. MRI revealed a right-sided extra-axial cerebellopontine angle lesion, leading to surgical resection. Histopathological analysis confirmed the presence of vestibular schwannoma with glandular elements, indicating metastasis from her breast cancer. Staging imaging subsequently revealed advanced oncologic spread.
What made this case unusual
This case highlights tumor-to-tumor metastasis involving vestibular schwannoma, a rare phenomenon where a known malignancy metastasizes to a benign tumor.
Diagnostic / clinical pearl
Clinicians should consider the possibility of tumor-to-tumor metastasis in patients with vestibular schwannoma who have a history of systemic malignancy.
Why it matters
Understanding the mechanisms of tumor-to-tumor metastasis can enhance the management of patients with concurrent malignancies and benign tumors.