Endovascular intervention for acute stroke in the very late window: A meta-analysis of 90-day mRS and procedural outcomes.

In 30 seconds

This meta-analysis evaluated the effectiveness of Endovascular Therapy (EVT) for ischemic stroke patients treated beyond 24 hours. The analysis included various studies and found that EVT significantly improved functional independence (38% vs. 10%, p < 0.05) despite an increased risk of symptomatic intracranial hemorrhage. The study highlights the importance of patient selection in this context.

Key findings

• EVT improved functional independence in patients treated beyond 24 hours (38% vs. 10%, p < 0.05).
• There was an increased risk of symptomatic intracranial hemorrhage with EVT.
• Mortality outcomes showed significant improvement in some studies (p < 0.05).
• Most studies reported no statistically significant differences in other outcomes (p > 0.05).

Why it matters

Understanding the potential benefits and risks of EVT in very late windows is crucial for clinicians managing acute ischemic stroke, as it may influence treatment decisions and patient outcomes.