Effects of bupropion and repetitive transcranial magnetic stimulation (rTMS) on sexual function, depression severity and cognitive performance in individuals with major depressive disorder - results from a double-blind, sham-controlled randomized intervention.
Amir Keshavarzi, Samaneh Zare Arandi, Mohammad Ahmadpanah et al.
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In 30 seconds
This randomized controlled trial investigated the effects of adjuvant repetitive transcranial magnetic stimulation (rTMS) on sexual function, depression severity, and cognitive performance in 40 inpatients with major depressive disorder (MDD) and sexual dysfunction. Results indicated that female sexual function improved significantly with active rTMS compared to sham treatment, while male sexual dysfunction and depression severity improved regardless of treatment condition. Cognitive performance also showed greater improvement in the active rTMS group.
Key findings
- Female sexual function improved significantly with active rTMS compared to sham treatment.
- Male sexual dysfunction decreased over time, regardless of the treatment condition.
- Depression severity decreased over time, irrespective of the study condition.
- Cognitive functions improved more in the active rTMS condition than in the sham group.
Why it matters
Understanding the impact of rTMS on sexual function in females with MDD is crucial, as sexual dysfunction can significantly affect quality of life. This study suggests that rTMS may enhance treatment outcomes for this population.